The dhatus form the basic stuff of the body tissues. These are of two categories Sthayee & Asthayee & generic types of these dhatus are 7. The presence of Sthayee dhatus controls the architecting of Asthayee dhatus throughout life from the available nutrients in the human system with the help of Agni, transporting mechanisms.

If due to deficiency of any nutrition/ in any chronic disease condition any kinds of dhatu get depleted then with the help of Rasayana therapy the process of formation of that particular dhatu/ dhatus is stimulated.

These Sthayee dhatus are stem cell in modern terms & in Ayurveda system of medicines the applied aspect of this concept is elaborately discussed & used therapeutically & as preventive measures for various diseases & as an anti-ageing modality.