So we have all those impressions as our memory, in our storehouse of information's from higher mental level to lower physical level that might be genes / molecular levels in modern biological sciences thru which we go thru during this universal phenomenon.

As Ayurveda believe in this concept 'YATHA PINDE TATHA BRAHAMANDE" so more importance is given on balancing the internal factors [physiological & pathological are same i.e. vata-pitta-kapha], this is also documented in managing the cases of tuberculosis, till date this area is not explored on modern parameters.

In view of Ayurveda every type of lower organisms are inside our system but they only create diseases when imbalance in between VPK [doshas] get manifested due to indulgence in the way & contents of living-thinking& eating that vitiated one -two /all the doshas & that imbalance effect mainly that organ/ system where is KH-VAIGUNYA [constitutionally imbalance of VPK, Kh- means five fundamental elements, Vaiguna means physiological-anatomical abrasions], so considering these facts if look to find the new molecules & targets by using the drugs documented in Ayurveda classics , that may solve this complex problem, may be first step to open new approach.

As in past anti - malarial dugs developed from the herbal source. Now we can take integral step by using not only the herbs but also the mechanics of pathogenesis.

In case of Rajyakshma and other complex diseases also a detailed description about etiological manifestation of disease - symptoms' complex & treatment against each symptom is documented.